12-O-Methylcarnosic acid

Research use only, not for human use.

12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM.12-O-Methylcarnosic acid has antioxidant activity, it is effective preventing gastric lesions.?

12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM.12-O-Methylcarnosic acid has antioxidant activity, it is effective preventing gastric lesions.?12-O-Methylcarnosic acid can suppress melanin production with downregulation of tyrosinase expression in HMV-II melanoma cells.12-O-Methylcarnosic acid may have anti-diabetic activity, it is able to significantly activate peroxisome proliferator-activated receptor (PPAR)γ.

12-O-Methylcarnosic acid (12-Methoxycarnosic acid; 5 μM) inhibits androgen-dependent proliferation of LNCaP cells as 66.7%. 12-O-Methylcarnosic acid shows antimicrobial activity against S. aureus at 78 μg/mL.

——

——

Endocrinology/Hormones

Reductase

5-α reductase

——

——

62201-71-2

346.46

C21H30O4

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (144.32 mM)

[H][C@@]12CCc3cc(C(C)C)c(OC)c(O)c3[C@]1(CCCC2(C)C)C(O)=O

——

(-20℃)

With Ice Pack

≥ 2 years